BioAdvanced 2-In-1 Systemic Rose & Flower Care feeds plus protects roses, flowers, and shrubs against listed insects in one easy step. It controls Aphids, Japanese Beetles (adult), Leafminers, Whiteflies and other listed pests. As a fertilizer, 2-In-1 Systemic Rose & Flower Care granules is absorbed through roots to promote strong roots and beautiful blooms. Its rainproof protection lasts up to 8 weeks. And it is easy to use. Just measure, sprinkle, work into soil, then water in. Rose and flower care has never been easier. This 5 lb bottle treats up to 18 rose bushes. BioAdvanced. Get More From The Blue Bottle. Not for sale in AR, AZ, DC, GA, LA, ME, MN, MS, MT, ND, NE, NM, NV, OR, RI, VA, VT, WI, WV, WY, See Notes for FL Restrictions. Active Ingredients: 1.5% Acephate. EPA Registration Number: 192-211-92564