This Glucosamine Chondroitin Triple Strength? formula with 50mcg of Vitamin D includes Joint Shield 5-LOXIN Advanced** a clinically studied herbal extract that has been shown to improve joint comfort in 7 days with significant improvement over time.*? This Osteo Bi-Flex joint supplement formula also includes Vitamin D to help support immune and bone health.* Glucosamine chondroitin an ingredient essential for the maintenance of joint cartilage and comfortable joint movement provides additional joint support to nourish and strengthen your joints for the long term.* Osteo Bi-Flex is the #1 pharmacist-recommended *** joint care supplement brand built on quality and innovation. With a focus on providing high-quality joint supplements that fulfill a variety of needs Osteo Bi-Flex is a trusted brand committed to providing products to support joint comfort mobility and flexibility.*